B.S. (1992) Massachusetts Institute of Technology
M.S. (1994) University of Texas
Ph.D. (1996) University of Texas
Bioactive and biomimetic biomaterials, tissue engineering, nanotechnology, drug delivery
Email: jwest@rice.edu
Phone: 713-348-5955
Office: W100E GRB Hall
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Jennifer West
Isabel C. Cameron Professor of Bioengineering
My research in biomaterials and tissue engineering focuses on the synthesis development and application of novel biofunctional materials and on the use of biomaterials and engineering approaches to study biological problems. Several of the projects ongoing in my laboratory are described below.
Tissue Engineered Vascular Grafts: There is tremendous need for materials for small diameter vascular grafts. Synthetic materials have not proved suitable, and tissue transplantation is limited. Tissue engineering may provide an answer. My laboratory is approaching this problem from two directions; synthesis of novel scaffold materials that mimic extracellular matrix and genetic manipulation of the cells seeded into these scaffolds. The scaffold materials under development provide signals to promote cell adhesion, to control synthesis of matrix proteins, to regulate cell growth, and to allow degradation of the polymer as new tissue forms. The goals for genetic engineering of smooth muscle and endothelial cells are to reduce thrombosis and improve the mechanical properties of the engineered arteries.
NO-Releasing Polymers: Nitric oxide (NO) has been shown to have anti-thrombotic activity and to inhibit smooth muscle cell proliferation. Thus, NO may be useful in the prevention of restenosis, a frequent complication of procedures such as balloon angioplasty that is related to thrombosis and smooth muscle cell proliferation. My laboratory is developing novel biomaterials that produce NO for sustained periods under physiological conditions. In addition to the potential therapeutic applications, these materials can be utilized as a powerful new tool to allow us to investigate the effects of nitric oxide on cells and tissues.
Mechanisms of Restenosis: Thin hydrogel coatings can be used to prevent thrombosis and isolate the arterial wall from blood contact after injury. When this is done after angioplasty procedures in animals, restenosis is virtually eliminated. To gain insight into the roles of factors derived from thrombosis and blood, local drug delivery approaches can be combined with arterial coatings to provide exposure to these factors individually and at known levels. Through this, I hope to gain unique insight into the biological mechanisms involved in restenosis and arterial wound healing.
Medical Applications of Metal Nanoshells: Nanoshells are a new type of nanoparticle with tunable optical properties. For medical applications, these particles can be designed to strongly absorb or scatter light in the near infrared where tissue and blood are relatively transparent. In a cancer therapy application, nanoshells are designed to absorb light and convert the energy to heat for tumor destruction. By conjugating antibodies or peptides to the nanoshell surfaces, binding of nanoshells can be targeted to cancerous cells, and subsequent exposure to near infrared light results in specific and localized destruction of the cancerous cells. A photothermally modulated drug delivery system, optically-controlled valves for microfluidics devices, and a rapid whole blood immunoassay are also under development using nanoshells.
Selected Publications
Article
Gonzalez, A.L., Gobin, A.S., West, J.L., McIntire, L.V., Smith, C.W. "Integrin interactions with immobilized peptides in polyethylene glycol diacrylate hydrogels." Tissue Engineering, 10 (2004): 1775-86.
O?Neal, D.P., Hirsch, L.R., Halas, N.J., West, J.L. "Nanoshell-assisted photothermal ablation of colon carcinoma-derived tumors in mice." Cancer Lett, 209 (2004): 171-6.
Sayes CM, Fortner JD, Lyon D, Boyd AM, Ausman KD, Guoh W, Tao YJ, Sitharaman B, Wilson LJ, West JL, Colvin VL "The differential cytotoxicity of water-soluble fullerenes.." Nano Letters, 4 (2004): 1881-7.
Elbjeirami, W.M., West, J.L. "Co-culture of endothelial cells with VEGF-transfected smooth muscle cells for formation of capillary networks." Tissue Engineering (2005).(In Press)
DeLong, S.A., Gobin, A.S., West, J.L. "Covalently immobilized gradients of RGD to direct cell alignment and migration." J. Cont. Rel. (2005).(In Press)
Sayes, C.M., Liang, F., Hudson, J.L., Mendez, J., Guo, W., Beach, J.M., Moore, V.C., Doyle, C.D., West, J.L., Billups, W.E., Ausman, K.D., Colvin, V.L. "Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro." Toxicol. Lett. (2005).(In Press)
Loo, C., Hirsch, L., Lee, M.H., Chang, E., West, J., Halas, N., Drezek, R. "Gold nanoshell biocomjugates for molecular imaging in living cells." Optics Lett., 30 (2005): 1012-4.
Myler, H.A., Lipke, E.A., Rice, E.E., West, J.L. "Heparanase neutralization inhibits bFGF release and neointima formation." J. Biochem. (2005).(In Press)
DeLong, S.A., Moon, J.J., West, J.L. "Immobilized gradients of bFGF for directed cell migration." Biomaterials, 26 (2005): 3227-34.
Loo, C., Lowery, A., Halas, N., West, J., Drezek, R. "Immunotargeted Nanoshells for Integrated Cancer Imaging and Therapy." NanoLetters, 5 (2005): 709-11.
Lowery, A., Gobin, A.M., Halas, N.J., West, J.L. "Immunotargeted nanoshells for photothermal tumor ablation." Int. J. Nanomed. (2005).(In Press)
Hahn, M.S., Miller, J.S., West, J.L. "Laser scanning lithography for surface micropatterning on hydrogels." Adv. Mater. (2005).(In Press)
Lipke, E.A., West, J.L. "Localized delivery of nitric oxide from hydrogels inhibits neointima formation in a rat carotid balloon injury model." Acta Biomaterialia, 1 (2005): 597-606.
Hirsch, L.R., Gobin, A.M., Lowery, A., Drezek, R.A., Halas, N.J., West, J.L. "Metal nanoshells: diagnostic and therapeutic applications of nanotechnology." Ann. Biomed. Eng. (2005).(In Press)
Jun, H.W., West, J.L. "Modification of polyurethaneurea with PEG and YIGSR peptide to enhance endothelialization without platelet adhesion." J. Biomed. Mater. Res., 72B (2005): 171-6.
Sayes, C.M., Gobin, A.M., Ausman, K.D., Mendez, J., West, J.L., Colvin, V.L. "Nano-C60 cytotoxicity is due to lipid peroxidation." Biomaterials, 26 (2005): 7587-95.
Bohl Masters KS, Lipke EA, Rice EEH, Liel MS, Myler HA, Zygourakis C, Tulis DA, West JL. "Nitric oxide-generating hydrogels inhibit neointima formation.." J Biomater Sci Polymer Ed, 16 (2005): 659-72.
Sershen, S.R., Ng, M.A., Halas, N.J., Beebe, D., West, J.L. "Optically controlled valves for microfluidics devices." Advanced Materials, 17 (2005): 1366-8.
Chang, E., Miller, J.S., Sun, J., Yu, W.W., Drezek, R., West, J.L. "Protease-activated quantum dot probes." Biochem. Biophys. Res. Comm., 334 (2005): 1317-21.
Lee, S.H., Miller, J.S., Moon, J.J., West, J.L. "Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration." Biotech. Prog. (2005).(In Press)
Hirsch, L.R., Halas, N.J., West, J.L. "Whole-blood immunoassay facilitated by gold nanoshell-conjugate antibodies." Methods Mol. Biol., 303 (2005): 101-12.
Jun, H.W., West, J.L. "Design of a YIGSR peptide modified polyurethaneurea to enhance endothelialization." J. Biomat. Sci. Polymer Ed, 15:73-94.
Myler, H.A., Rice, E.E.H., Lipke, E.A., West, J.L. "Heparanase inhibition prevents bFGF liberation from the ECM and subsequent intimal thickening." Proc. Natl. Acad. Sci.(Submitted)
Gobin, A.M., Sershen, S.R., Watkins, D., Halas, N.J., Drezek, R.A., West, J.L. "Nanoshells as an exogenous near infrared absorber to facilitate laser tissue welding." Lasers Surg. Med. (2005), 37: 123-9.
Patel, P.N., Gobin, A.S., West, J.L., Patrick, C.W. "Poly (ethyleneglycol) hydrogel system supports preadipocyte viability, adhesion, and proliferation.." Tissue Engineering (2005), 11: 1498-505.
Jun, H.W., West, J.L. "Endothelialization of microporous, bioactive polyurethane grafts." Tissue Engineering, 11 ((2005)): 1133-40.
Jun, H.W., Taite, L.J., West, J.L. "Nitric oxide-producing polyurethanes." Biomacromolecules, 6 ((2005)): 838-44.
Loo, C., Lin, A., Hirsch, L., Lee, M.H., Barton, J., Halas, N., West, J., Drezek, R. "Nanoshell-enabled photonics-based imaging and therapy of cancer." Cancer Res. Treat, 3:33-40 (04).
Hirsch, L.R., Jackson, J.B., Lee, A., Halas, N.J., West, J.L. "A whole blood immunoassay using gold nanoshells." Analyt. Chem, 75 (2003): 2377-81.
Jackson, J.B., Westcott, S.L., Hirsch, L.R., West, J.L., Halas, N.J. "Controlling the surface enhanced Raman effect via the nanoshell geometry." Appl. Phys. Lett, 82 (2003): 257-9.
Gobin, A.S., West, J.L. "Effects of epidermal growth factor on fibroblast migration through biomimetic hydrogels." Biotech. Prog (2003): 10.1021/bp0341390.
Drezek, R., West, J., Halas, N. "Emerging optical technologies for noninvasive functional and molecular imaging: Applications for breast cancer." Breast Diseases, 14 (2003): 18-20.
West, J.L., Halas, N.J. "Engineered Nanomaterials for Biophotonics Applications: Improving Sensing, Imaging, and Therapeutics." Ann. Rev. Biomed. Eng, 5 (2003): 285-92.
Elbjeirami, W.M., Yonter, E.O., Starcher, B., West, J.L. "Enhancing mechanical properties of engineered tissues via lysyl oxidase crosslinking activity." , 66 (2003): 513-21.
Myler, H.A., Rice, E.E.H., Lipke, E.A., West, J.L. "Heparanase inhibition prevents bFGF liberation from the ECM and subsequent intimal thickening." Circulation (2003).(Submitted)
Drezek, R., West, J., Halas, N. "Emerging Optical Technologies for Breast Cancer Imaging." a chapter in Advances in Diagnosis and Treatment of Breast Disease, (2004).
West, J.L. "Bioactive Hydrogels." A chapter in Scaffolding in Tissue Engineering (2004).
Gobin, A.S., West, J.L. "Val-Ala-Pro-Gly, an elastin-derived non-integrin ligand: Smooth muscle cell adhesion and specificity." J. Biomed. Mater. Res, 67 (2003): 255-9.
Schmedlen, R.H., Gobin, A.S., Elbjeirami, W.M., West, J.L. "Tissue Engineered Vascular Grafts." Clin. Plast. Surg, 30 (2003): 507-17.(In Press)
West, J.L. "Modification of Polymers with Bioactive Peptides." Methods in Biopolymers (2003).
O¿Neal, D.P., Hirsch, L.R., Halas, N.J., West, J.L. "Nanoshell-assisted photothermal ablation of colon carcinoma-derived tumors in mice." Science (2003).(Submitted)
Hirsch, L.R., Stafford, R.J., Sershen, S.R., Halas, N.J., Hazle, J.D., West, J.L. "Nanoshell-assisted tumor ablation using near infrared light under magnetic resonance guidance." Proc. Natl. Acad. Sci. USA, 100 (2003): 113549-54.(In Press)
West, J.L. Nature Materials "Pulsed Polymers." News & Views, 2 (2003): 1-2.
Sershen, S.R., Ng, M.A., Halas, N.J., Beebe, D., West, J.L. "Optically controlled valves for microfluidics devices." Nature Materials (2003).(Submitted)
Book chapter
Drezek, R., West, J., Halas, N. "Emerging Optical Technologies for Breast Cancer Imaging." Advances in Diagnosis and Treatment of Breast Disease.(In Press)
Stephens-Altus, J.S., West, J.L. ¿Nanotechnology for Tissue Engineering¿, a chapter in Advances in Tissue Engineering, Polak ed., Imperial College Press, 2008.
Miller, J.S., West, J.L "Rapid Prototyping of Hydrogels to Guide Tissue Formation." Bio-materials and Prototyping Applications in Medicine (2007): 49-65.
Drezek, R.A., Halas, N.J., West, J.L. "Optical Imaging for In Vivo Assessment of Tissue Pathology." Frontiers of Engineering (2007): 65-72.
Bergmann, N.M., West, J.L "Histogenesis in Three-Dimensional Scaffolds." Biomaterials for Regenerative Medicine (2007): 674-91.
"Bioactive Materials." Encyclopedia of Biomaterials and Biomedical Engineering (2003).
Bergmann, N.M., West, J.L "Histogenesis in Three-Dimensional Scaffolds." Biomaterials for Regenerative Medicine (2007): 674-91.
Conference paper
"WTEC Panel Report on Tissue Engineering Research." Academic Press (2003).(Submitted)
Other
Masters, K.S., Lipke, E.A., Rice, E.E.H., Liel, M.S., Myler, H.A., West, J.L. "Effects of S-nitrosocysteine on endothelial and smooth muscle cell behaviors and neointima formation." Biochem. Biophys. Res. Comm (2003).(In Press)
Sershen, S.R., Bankson, J.R., Hazel, J.J., Halas, N.J., West, J.L. "Light-triggered protein release from hydrogel drug delivery systems." Nature Materials.(In Revision)
Hill-West, Chowdhury, Sawhney, Pathak, Dunn, Hubbell "Prevention of Post-Operative Adhesions in the Rat by In Situ Photopolymerization of Bioresorbable Hydrogel Barriers." Obstetrics and Gynecology, 83 (1994): 59-64.
Masters, K.S., Lipke, E.A., Rice, E.E.H., Liel, M.S., Myler, H.A., West, J.L. "Effects of S-nitrosocysteine on endothelial and smooth muscle cell behaviors and neointima formation." Biochem. Biophys. Res. Comm..(In Press)
Hill-West, Chowdhury, Dunn, Hubbell "Efficacy of a Hydrogel Barrier, Oxidized Regenerated Cellulose and Hyaluronic Acid in the Prevention of Ovarian Adhesions in a Rabbit Model." Fertility and Sterility, 62 (1994): 630-634.
Hill-West, Chowdhury, Slepian, Hubbell "Inhibition of Thrombosis and Intimal Thickening by Interfacially Photopolymerized Hydrogel Barriers." Proc. Natl Acad. Sci., USA91 (1994): 5967-5971.
Refereed Article
Moon, J.J., West, J.L. ¿Vascularization of engineered tissues: approaches to promote angiogenesis in biomaterials¿, Curr. Top. Med. Chem., 8:300-10, 2008.
Lee, S.H., Moon, J.J., West, J.L. ¿Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration¿, Biomaterials, 29:2962-8, 2008.
Bikram, M., West, J.L. "Thermo-responsive systems for controlled drug delivery", Expert Opin Drug Deliv., 5:1077-91, 2008.
Taite, L.J., Yang, P., Jun, H.W., West, J.L. ¿Nitric oxide-releasing polyurethane-PEG copolymer containing the YIGSR peptide promotes endothelialization with decreased platelet adhesion¿, J. Biomed. Mater. Res., 84:108-16, 2008.
Gobin, A.M., Lee, M.H., Halas, N.J., James, W.D., Drezek, R.A., West, J.L "Near-Infrared Resonant Nanoshells for Combined Optical Imaging and Photothermal Cancer Therapy." NanoLetters, 7 (2007): 1929-34.
Tsang, V.L., Chen, A.A., Cho, L.M., Jadin, K.D., Sah, R.L., DeLong, S., West, J.L., Bhatia, S.N "Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels." FASEB J, 21 (2007): 790-801.
Hahn, M.S., McHale, M.K., Wang, E., Schmedlen, R.H., West, J.L "Physiologic pulsatile flow bioreactor conditioning of poly(ethylene glycol)-based tissue engineered vascular grafts." Ann. Biomed. Eng, 35 (2007): 190-200.
Lee, S.H., Moon, J.J., Miller, J.S., West, J.L. "Poly(ethylene glycol) hydrogels conjugated with a collagenase-sensitive fluorogenic substrate to visualize collagnease activity during three-dimensional cell migration." Biomaterials, 28 (2007): 3163-70.
Bikram, M., Fouletier-Dilling, C., Hipp, J.A., Gannon, F., Davis, A.R., Olmsted-Davis, E.A., West, J.L "Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells." Ann. Biomed. Eng, 35 (2007): 796-807.
Buxton, A.N., Zhu, J., Marchant, R., West, J.L., Yoo, J.U., Johnstone, B "Design and characterization of poly(ethylene glycol) photopolymerizable semi-interpenetrating networks for chondrogenesis of human mesenchymal stem cells." Tiss. Eng, 13 (2007): 2549-60.
Moon, J.J., Lee, S.H., West, J.L "Synthetic biomimetic hydrogels incorporated with ephrin-A1 for therapeutic angiogenesis." Biomacromolecules, 8 (2007): 42-9.
Moon, J.J., Hahn, M.S., Kim, I., Nsiah, B.A., West. J.L. Micropatterning of Poly(Ethylene Glycol) Diacrylate Hydrogels with Biomolecules to Regulate and Guide Endothelial Morphogenesis, Tissue Eng Part A, In Press, 2008, PMID: 18803481.
Bernardi, R.J., Lowery, A.R., Thompson, P.A., Blaney, S.M., West, J.L. ¿Immunonanoshells for targeted photothermal ablation in medulloblastoma and glioma: an in vitro evaluation using human cell lines¿, J. Neuroonc., 86:165-72, 2008.
Gobin, A.M., Moon, J.J., West, J.L. ¿EphrinA I-targeted nanoshells for photothermal ablation of prostate cancer cells¿, Int J Nanomedicine, 3:351-8, 2008.
Bellows, C.F., Jian, W., McHale, M.K., Cardenas, D., West, J.L., Lerner, S.P., Amiel, G.E. ¿Blood vessel matrix: a new alternative for abdominal wall reconstruction¿, Hernia, 12:351-8, 2008.
Gonzalez, A.L., El-Bjeirami, W., West, J.L., McIntire, L.V., Smith, C.W "Transendothelial migration enhances integrin-dependent human neutrophil chemokinesis." J. Leukoc. Biol, 81 (2007): 686-95.
Bikram, M., Gobin, A.M., Whitmire, R.E., West, J.L "Temperature-sensitive hydrogels with SiO2-Au nanoshells for controlled drug delivery." J. Control Rel, 123 (2007): 219-27.
Refereed Conference Paper
Jun, H.W., West, J.L. "Development of YIGSR Peptide-Modified Polyurethaneurea To Enhance Endothelialization." Houston Society for Engineering in Medicine and Biology (April 2003).(Submitted)
L. R. Hirsch, J. B. Jackson, A. Lee, N. J. Halas, J. L. West. "A Rapid Whole Blood Immunoassay Using Metal Nanoshells." 25th Annual International IEEE Engineering in Medicine and Biology Society (Sept. 2003).(Submitted)
Jun, H.W., West, J.L. "Polyurethaneurea Modified with PEG and YIGSR to Enhance Endothelialization without Platelet Adhesion." Biomedical Engineering Society (Oct.2003).(Submitted)
Schmedlen, R.H., West, J.L. "Tissue Engineered Vascular Grafts: Culture in Pulsatile Flow Bioreactor Systems using Elastic Hydrogel Scaffolds." Biomedical Engineering Society (Oct. 2003).(Submitted)
Taite, L.J., Lipke, E.A., West, J.L. "Poly(ethylene glycol) copolymers for sustained nitric oxide delivery." Biomedical Engineering Society (Oct. 2003).(Submitted)
Lipke, E.A., Masters, K.S., West, J.L. "Local delivery of nitric oxide for prevention of neointimal hyperplasia and promotion of endothelialization." Biomedical Engineering Society (Oct. 2003).(Submitted)
Lau, I., Elbjeirami, W.M., Starcher, B.C., West, J.L. "Enhancing Mechanical Properties of Vascular Grafts through Increased Expression of Lysyl Oxidase." Biomedical Engineering Society (Oct. 2003).(Submitted)
Lau, I. West, J.L. "A Novel Collagen-based Gene Delivery system with Polyethylenimine-DNA Complexes." Biomedical Engineering Society (Oct. 2003).(Submitted)
Lipke, E.A., Masters, K.S., Myler, H.A., West, J.L. "Nitric oxide generating hydrogels inhibit neointima formation." American Heart Association (Nov. 2003).(Submitted)
DeLong, S.A., West, J.L. "Tethered basic fibroblast growth factor increases cell proliferation." Society for Biomaterials (May 2003).(Submitted)
Schmedlen, R.H., West, J.L. "Poly(ethylene glycol) hydrogel scaffolds for vascular tissue engineering using pulsatile flow bioreactors." Society for Biomaterials (May 2003).(Submitted)
L. R. Hirsch, R. J. Stafford, J. A. Bankson, S. R. Sershen, R. E. Price, J. D. Hazle, N. J. Halas, & J. L. West. "Photothermal Tumor Therapy using Metal Nanoshells." Society for Biomaterials (May 2003).(Submitted)
Lipke, E.A., Masters, K.S., Dittrich, C.R., West, J.L. "Nitric oxide delivery from hydrogels enhances endothelial cell proliferation." Society for Biomaterials (May 2003).(Submitted)
Lipke, E.A., Masters, K.S., Myler, H.A., West, J.L. "Local nitric oxide delivery for prevention of restenosis." Society for Biomaterials (May 2003).(Submitted)
Jun, H.W., West, J.L. "Bulk Modification of Polyurethanurea with Cell Adhesion Peptides." Society for Biomaterials (May 2003).(Submitted)
Hirsch, L.R., Jackson, J.B., Halas, N.J., West, J.L. "A rapid whole blood immunoassay based on nanoshell aggregation." Society for Biomaterials (May 2003).(Submitted)
Sershen, S.R., Halas, N.J., West, J.L. "Optically responsive nanocomposites." ACS Meeting (March 2003).(Submitted)
Hirsch, L.R., Stafford, R.J., Price, R.E., Hazle, J.D., Halas, N.J., West, J.L. "Targeted hyperthermic cancer therapy using immunoconjugated nanoshells." Summer Bioengineering Conference (June 2003).(Submitted)
Elbjeirami, W.M., Lau, I., Starcher, B.S., West, J.L. "Enhancing engineered tissues through gene therapy." Summer Bioengineering Conference (June 2003).(Submitted)
R. J. Stafford, L. R. Hirsch, R. E. Price, B. Rivera, S. R. Sershen, J. L. West, J. D. Hazle "Magnetic Resonance-Guided Extracorporeal Laser Mediated Thermal Therapy of Intratumoral Gold Nanoshell Particle Injections." International Society for Magnetic Resonance in Medicine 11th Scientific Meeting (July 2003).(Submitted)
Lipke, E.A., Masters, K.S., Myler, H.A., West, J.L. "Delivery of NO from Bioactive Hydrogels for Prevention of Restenosis." Gordon Research Conference on Biomaterials and Biocompatibility (July 2003).(Submitted)
Taite, L.J., Lipke, E.A., West, J.L. "Poly(ethylene glycol) copolymers for sustained nitric oxide delivery." Houston Society for Engineering in Medicine and Biology (April 2003).(Submitted)
Lau, I., Elbjeirami, W.M., Starcher, B.C., West, J.L. "Enhancing Mechanical Properties of Vascular Grafts through Increased Expression of Lysyl Oxidase." Houston Society for Engineering in Medicine and Biology (April 2003).(Submitted)
Presentations
Invited Talk
"American Physical Society, Opportunities in Biological Physics Symposium. Tissue Engineering and Regenrative Medicine.". (2007)
"Biomimetic Materials in Vascular Tissue Engineering." Department of Bioengineering, UCLA. (2008)
"Department Seminar." MIT. (2003)
"Department seminar." Duke University. (04)
"IEEE Nanoscale Devices and Interfaces.". (2005)
"BEACON, Biomimetic Strategies in Tissue Engineering.". (2007)
"Department Seminar." Harvard. (2003)
"Department seminar." Imperial College. (04)
"Diagnostic and Therapeutic Applications of Nanotechnology." Emory University School of Medicine, Atlanta, Georgia. (2008)
"Elastomers and Gels Gordon Research Conference.". (2005)
"Department Seminar." University of Alabama at Birmingham. (2003)
"Department seminar." Baylor College of Medicine Vascular Surgery. (04)
"FDA Science Symposium.". (2005)
"Medical Applications of Nanotechnology." Congressional Caucus on Nanotechnology, . (2008)
"The Academy of Medicine, Engineering, and Science of Texas Annual Meeting, Cardiovascular Engineering Session, Biomimetic Strategies in Vascular Tissue Engineering.". (2007)
"Biomimetic Biomaterials." The Academy of Medicine, Engineering and Science of Texas (TAMEST), Houston, TX. (January 2008)
"Department Seminar." UC San Diego. (2003)
"International Society for Applied Cardiovascular Biology.". (04)
"NCI NCAB.". (2005)
"North American Vascular Biology Organization Annual Meeting, Biomimetic Hydrogels that Mimic the Vascular Extracellular Matrix.". (2007)
"American Society for Matrix Biology.". (04)
"Biomimetic Strategies in Vascular Tissue Engineering." Experimental Biology 2008, San Diego, California. (April 2008)
"Controlled Release Society Annual Meeting, Biomimetic Strategies in Tissue Engineering." 2007.
"Department Seminar." CalTech. (2003)
"NIH NIBIB Council.". (2005)
"American Society for Gene Therapy.". (04)
"Association of Clinical and Laboratory Physician-Scientists Annual Meeting, Diagnostic Applications of Nanotechnology.". (2007)
"Biomimetic Strategies in Vascular Tissue Engineering." The 235th American Chemical Society National Meeting, New Orleans, Louisiana. (April 2008)
"Department Seminar." Washington University. (2003)
"Whitaker Summit.". (2005)
"Department Seminar." Purdue. (2003)
"Designing Synthetic Polymers to Mimic the ECM." Department of Biomedical Engineering Distinguished Lecturer Series, University of California at Irvine. (November 2008)
"Mayo Clinic.". (2005)
"Texas Nanotechnology Conference, Diagnostic and Therapeutic Applications of Nanotechnology.". (2007)
"Association of University Technology Managers Annual Meeting, Diagnostic and Therapeutic Applications of Nanotechnology.". (2007)
"Department Seminar." Los Alamos National Laboratory. (2003)
"M.D. Anderson Grand Rounds.". (2005)
"Nanotechnology for Cancer." 2008 Texas Life Science Conference Oncology Forum, Houston, Texas. (November 2008)
"Department Seminar." University of Colorado. (2003)
"Frontiers of Engineerring Symposium." National Academy of Engineering, . (04)
"Medical Applications of Nanotechnology." 11th Annual Japanese-American Kavli Frontiers of Science Symposium, Irvine, California. (December 2008)
"National Cancer Institute Symposium on Nanomedicine, Diagnostic and Therapeutic Applications of Nanotechnology.". (2007)
"Society for Biomaterials.". (2005)
"Biomedical Engineering Society.". (2005)
"Department Seminar." University of Pennsylvania. (2003)
"Georgia Institute of Technology, Bioengineering Department Seminar.". (2007)
"Nanotechnology and Cancer." National Cancer Institute Advisory Board Meeting, . (04)
"Bioengineering Presentation." Rice Alumni College. (2003)
"Biomedical Materials at the Edge Challenges in the Convergence of Technologies." National Cancer Institute Advisory Board Meeting. (04)
"NAE Frontiers of Engineering.". (2004)
"Purdue, Biomedical Engineering Department Seminar.". (2007)
"Bioengineering Presentation." American Chemical Society, . (2003)
"Breast Cancer Symposium.". (2005)
"University of Minnesota, Department of Pharmacology Seminar.". (2007)
"Bioemedical Engineering Society.". (2005)
"Histology in Tissue Engineering Workshop." Society for Biomaterials, . (2003)
"University of North Carolina, Center for Cancer Nanotechnology Excellence Seminar.". (2007)
"Baylor College of Medicine.". (2005)
"Bioengineering Presentation." NIH NIBIB Council Meeting, . (2003)
"Bioengineering Presentation." CHI BioMEMS and Nanotech World Symposium, . (2003)
"Texas A&M.". (2005)
"Bioengineering Presentation." NSF-Yokohama International Workshop on Nanotechnology, . (2003)
Keynote Speaker
"Nanotechnology for Cancer Therapy: Translating Cutting Edge Research to the Clinic." 2008 Translational Biomaterial Research Symposium, Society for Biomaterials, Atlanta, Georgia. (September 2008)
Other
"The Next Generation." Biomaterials, . (04)
Session Chair
Session Chair and Presenter. "Nanotechnology for Cellular Imaging." Tissue Engineering & Regenerative Medicine International Society (TERMIS), San Diego, California. (December 2008)
Workshop
"Building Bridges Between Nanotechnology and Cancer Research.". (04)
Editorial Positions
Member of the Editorial Board, Journal of Biomaterials Science, (2003).
Associate Editor, Annals of Biomedical Engineering, (2003).
Other, Annual Reviews in Biomedical Engineering, (2003).
Other, Biomaterials, (2004).
Other, Advanced Materials, (2004).
Other, Journal of Biomedical Materials Research, (2004).
Other, Polymer, (2004).
Other, Biomacromolecules, (2004).
Other, Nanotechnology Letters, (2004).
Other, Circulation Science, (2004).
Associate Editor, Annals of Biomedical Engineering, (2004).
Member of the Editorial Board, Journal of Biomaterials Science, Polymer Edition, (2004).
Other, Nature Medicine, (2004).
Other, Nature Biotechnology, (2004).
Other, Nature Materials, (2004).
Other, Nature Drug Discovery, (2004).
Other, Journal of the american Chemical Society, (2004).
Other, Langmuir, (2004).
Other, Applied Biochemistry and Biotechnology, (2004).
Other, Biotechnology & Bioengineering, (2004).
Other, Tissue Engineering, (2004).
Other, Journal of Biomechanical Engineering, (2004).
Associate Editor, Annals of Biomedical Engineering, (2005).
Member of the Editorial Board, Technology in Cancer Research and Treatment, (2005).
Associate Editor, Annals of Biomedical Engineering, (2007).
Member of the Editorial Board, Journal of Biomaterials Science, Polymer Edition, (2007).
Member of the Editorial Board, Technology in Cancer Research and Treatment, (2007).
Associate Editor, Annals of Biomedical Engineering, (2006).
Associate Editor, Annals of Biomedical Engineering, (2008).
Member of the Editorial Board, Journal of Biomaterials Science, Polymer Edition, (2008).
Member of the Editorial Board, Technology in Cancer Research and Treatment, (2008).
Associate Editor, Dictionary of Nanoscience and Nanotechnology, (2011).
Member of the Editorial Board, Journal of Biomaterials Science, Polymer Edition, (2006).
Theses
Edward Yonter, Masters. "Gene Therapy Approaches to Alter the Mechanical Properties of Tissue Engineered Constructs." (2000).(Thesis or Dissertation Director)
Krystyn Masters, PhD. "Pharmacologically active materials for localized nitric oxide therapy." (2001).(Thesis or Dissertation Director)
Heather Myler, PhD. "Heparanase and Platelet Factor-4 Induce smooth Muscle Cell Proliferation and Migration via Basic Fibroblast Growth Factor Release from the Extracellular Matrix: Implications in the Restenosis Process." (2002).(Thesis or Dissertation Director)
Scott Sershen, PhD. "Applications of Photothermally Responsive Composite Materials." (2002).(Thesis or Dissertation Director)
Wafa Elbjerami, PhD. "Graduated." (2003).
Wafa Elberjiami, PhD. "Graduated." (2003).(Thesis or Dissertation Director)
Heather Myler, PhD. "Graduated." (2003).
Andrea Gobin, PhD. "Graduated." (2003).(Thesis or Dissertation Director)
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